Product IntroductionBioactivity英文名:
Odatroltide描述: Odatroltide is a nanoscale P-selectin inhibitor that serves as a nano-delivery system for 6,7-dihydroxyl-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid and KPAK to specifically target the thrombus.
体外活性: Odatroltide (1 nM) effectively down-regulates P-selectin expression. DHDMIQK(KAP) effectively inhibits platelet aggregation via down-regulating the expression of P-selectin. Odatroltide effectively inhibits platelet aggregations induced by TH, AA, ADP and PAF, which are correlated with the downregulation of P-selectin expression and with the scavenging of the free radicals[1].
体内活性: Odatroltide (0.01 nmol/kg) lyses the thrombus and inhibits thrombosis with a minimal[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year