化合物 AEG40826 T68262
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Product IntroductionBioactivity英文名: AEG40826描述: AEG40826 (HGS1029) is the hydrochloride salt of a small-molecule inhibito
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Product Introduction
Bioactivity
英文名: AEG40826
描述: AEG40826 (HGS1029) is the hydrochloride salt of a small-molecule inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins with potential antineoplastic activity. IAP inhibitor HGS1029 selectively inhibits the biological activity of IAP proteins, which may restore apoptotic signaling pathways; this agent may work synergistically with cytotoxic drugs to overcome tumor cell resistance to apoptosis. IAPs are overexpressed by many cancer cell types, suppressing apoptosis by binding and inhibiting active caspases-3, -7 and -9 via their BIR (baculoviral lAP repeat) domains.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: AEG 40826 | HGS-1029 | HGS 1029 | AEG-40826 | AEG408262 HCl. | AEG40826
Bioactivity
英文名: AEG40826
描述: AEG40826 (HGS1029) is the hydrochloride salt of a small-molecule inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins with potential antineoplastic activity. IAP inhibitor HGS1029 selectively inhibits the biological activity of IAP proteins, which may restore apoptotic signaling pathways; this agent may work synergistically with cytotoxic drugs to overcome tumor cell resistance to apoptosis. IAPs are overexpressed by many cancer cell types, suppressing apoptosis by binding and inhibiting active caspases-3, -7 and -9 via their BIR (baculoviral lAP repeat) domains.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: AEG 40826 | HGS-1029 | HGS 1029 | AEG-40826 | AEG408262 HCl. | AEG40826
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