化合物 AEG40826 T68262

Product Introduction
Bioactivity


英文名: AEG40826

描述: AEG40826 (HGS1029) is the hydrochloride salt of a small-molecule inhibitor of IAP (Inhibitor of Apoptosis Protein) family proteins with potential antineoplastic activity. IAP inhibitor HGS1029 selectively inhibits the biological activity of IAP proteins, which may restore apoptotic signaling pathways; this agent may work synergistically with cytotoxic drugs to overcome tumor cell resistance to apoptosis. IAPs are overexpressed by many cancer cell types, suppressing apoptosis by binding and inhibiting active caspases-3, -7 and -9 via their BIR (baculoviral lAP repeat) domains.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: AEG 40826 | HGS-1029 | HGS 1029 | AEG-40826 | AEG408262 HCl. | AEG40826

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途