化合物 RO5068760 T68267
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Product IntroductionBioactivity英文名: RO5068760描述: RO5068760 , a substituted hydantoin, is a potent, highly selective, non-
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Product Introduction
Bioactivity
英文名: RO5068760
描述: RO5068760 , a substituted hydantoin, is a potent, highly selective, non-adenosine triphosphate (ATP)-competitive MEK1/2 inhibitors. RO5068760 shows significant efficacy in a broad spectrum of tumors with aberrant mitogen-activated protein kinase pathway activation. In vitro, RO5068760 demonstrates MEK1 kinase inhibitory activity with an IC50 of 0.025 μM in a cRaf/MEK/ERK cascade assay RO5068760 showed superior efficacy in tumors harboring B-RafV600E mutation.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: RO-5068760. | RO-5068760 | RO 5068760 | RO5068760
Bioactivity
英文名: RO5068760
描述: RO5068760 , a substituted hydantoin, is a potent, highly selective, non-adenosine triphosphate (ATP)-competitive MEK1/2 inhibitors. RO5068760 shows significant efficacy in a broad spectrum of tumors with aberrant mitogen-activated protein kinase pathway activation. In vitro, RO5068760 demonstrates MEK1 kinase inhibitory activity with an IC50 of 0.025 μM in a cRaf/MEK/ERK cascade assay RO5068760 showed superior efficacy in tumors harboring B-RafV600E mutation.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: RO-5068760. | RO-5068760 | RO 5068760 | RO5068760
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