F129882-100mgFerrostatin-1 (Fer-1)
面议
- 阿拉丁
- 生产商
- F129882-100mg
- 现货
- 全国
规格 |
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耗材描述
- 分子式 C15H22N2O2
- 分子量262.35
属性
溶解性 |
|
存贮条件 | 储存温度2-8℃ |
描述
应用 | A potent inhibitor of non-apoptotic cell death induced by erastin call ferroptosis |
产品介绍 | Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM. |
备注 | Ferrostatin-1 (Fer-1) is a potent and selective inhibitor of ferroptosis with EC50 of 60 nM. |
生化机理 | Ferrostatin-1 (2 μM) prevents erastin-induced ferroptosis in cancer cells, as well as glutamate-induced cell death in postnatal rat brain slices. Ferrostatin-1 is a lipid ROS scavenger, with the N-cyclohexyl moiety serving as a lipo-philic anchor within biological membranes. Ferrostatin-1 Ferrostatin-1 is a potent inhibitor of non-apoptotic cell death induced by erastin call ferroptosis. Ferrostatin-1 prevents ferroptopic cell death in cancer cells and glutamate-induced toxicity in organotypic rat brain slices. It appears that Ferrostatin-1 controls lipid soluble ROS. |
别名 | ;3-Amino-4-cyclohexylaminobenzoic Acid Ethyl Ester; |
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