D129529-100mg&Daptomycin
面议
- 阿拉丁
- 生产商
- D129529-100mg
- 现货
- 全国
规格 |
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耗材描述
属性
敏感性 | 对热敏感 |
溶解性 | Soluble in water (100 mg/ml at 25 °C), ethanol (50 mM), methanol (5 mg/ml), DMSO (100 mM), and DMF. |
存贮条件 | 储存温度-20°C |
描述
应用 | Calcium-dependent lipopeptide antibiotic. |
产品介绍 | Daptomycin 是一种新型脂肽类抗生素。 |
备注 | Daptomycin is a novel lipopeptide antibiotic. |
生化机理 | Daptomycin is a lipopeptide antibiotic produced by Streptomyces roseosporus with reported in vitro bactericidal activity against gram-positive organisms. As a calcium-dependent antibiotic, Daptomycin has been reported to act on the cytoplasmic membrane and undergo a conformational change upon interaction with lipid membranes in a model system. After the conformational change occurs, the compound is inserted into the membrane and causes significant perturbations. Membrane depolarization and leakage occurs, causing death in susceptible organisms. |
别名 | 达托霉素;达妥霉素;Dapcin;Cubicin;LY146032; LY 146032; LY-146032 |
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