S129720-50mgSB415286
面议
- 阿拉丁
- 生产商
- S129720-50mg
- 现货
- 全国
规格 |
---|
耗材描述
- 分子式 C16H10ClN3O5
- 分子量359.72
- EC号 MFCD04039789
- MDL号 MFCD04039789
- PubChem编号 24278412
属性
溶解性 |
|
存贮条件 | 储存温度-20°C |
描述
产品介绍 | SB 415286 |
合法信息 | Sold for only research purposes |
备注 | SB415286 is a potent GSK3α inhibitor with IC50/Ki of 78 nM/31 nM with equally effective inhibition of GSK-3β. |
生化机理 |
SB 415286 is a potent and selective cell-permeable, ATP-competitive inhibitor of GSK3α with an IC50 value of 78 nM (similar potency for GSK3β) and a Ki value of 31 nM. 1 As a result of GSK3 inhibition, SB 415286 stimulates glycogen synthesis in the Chang human liver cell line with an EC50 value of 2.9 ?M. SB 415286 also protects primary neurons from death induced by the PI3-kinase pathway. |
别名 | 3-(3-chloro-4-hydroxyphenylamino)-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione;3-(3-chloro-4-hydroxyphenylamino)-4-(2-nitrophenyl)-1H-pyrrole-2,5-dione |
标识符号 |
![]() |
信号词 | Warning |
危害声明 | H315-H319-H335 |
警示性声明 | P261-P305 + P351 + P338 |
个人防护设备 | dust mask type N95 (US), Eyeshields, Gloves |
WGK德国 | 3 |
猜你喜欢
感兴趣产品