P127282-100mgSofosbuvir
面议
- 阿拉丁
- 生产商
- P127282-100mg
- 现货
- 全国
规格 |
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耗材描述
属性
溶解性 | DMSO |
存贮条件 | 储存温度-20°C |
描述
产品介绍 | Sofosbuvir (PSI-7977, GS-7977) 是一种 HCV的NS5B polymerase抑制剂,用于治疗慢性丙型肝炎病毒(HCV)的感染。 |
生化机理 | PSI-7977 is an investigational nucleotide analog currently in Phase 2 for treatment of chronic HCV infection. PSI-7851 is a mixture of two similar molecules, PSI-7976 and PSI-7977, which exist in PSI-7851 as isomers of each other. Once inside a liver cell, both molecules are rapidly converted to the same active triphosphate. Given the ability to more easily manufacture PSI-7977, and potentially advantageous in vitro characteristics, PSI-7977 was selected for further clinical development. Antiviral agents |
别名 | 索非布韦;索氟布韦;PSI-7977, GS-7977;N-[[P(S),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-methylethyl ester;PSI 7977;PSI-7977, GS-7977;N-[[P(S),2'R]-2'-Deoxy-2'-fluoro-2'-methyl-P-phenyl-5'-uridylyl]-L-alanine 1-methylethyl ester |
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