Daptomycin | 达托霉素 | MedChemExpress (MCE)
品牌 | 厂商性质 | 产地 | 货期 | 价格 |
---|---|---|---|---|
MedChemExpress (MCE) | 生产商 | 美国 | 现货 | 213 |
性能特点
Daptomycin 是一种脂肽类抗生素,具有体外快速杀除革兰氏阳性细菌的活性。
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
5 mg | 103060-53-3 | ¥213.00 | 询底价 |
MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务。
Daptomycin
CAS No. : 103060-53-3
MCE 国际站:Daptomycin
产品活性:Daptomycin 是一种脂肽类抗生素,具有体外快速杀除革兰氏阳性细菌的活性。
研究领域:Anti-infection
作用靶点:Bacterial | Antibiotic
In Vitro: Daptomycin has excellent in-vitro inhibitory and bactericidal activity against nafcillin-susceptible and resistant staphylococci (MIC90 less than or equal to 0.5 mg/L) and against enterococci (MIC90 less than or equal to 2.0 mg/L). Daptomycin is more active than vancomycin against the majority of isolated tested. With the exception of trimethoprim-sulphamethoxazole, daptomycin is the most active agent in vitro against enterococci, and is the most active against nafcillin-resistant staphylococci. Daptomycin and vancomycin show a marked increase in MIC when the inoculum is increased from 105 to 107 cfu/mL. Daptomycin is effective within a very narrow range of drug concentrations (from 0.125 to 2.0 tLg/mL) and is more active than other agents tested against S. faecalis. Daptomycin inhibits the formation of these nucleotide-linked intermediates.
In Vivo: At a dose of 10 mg/kg given twice daily, daptomycin reduces the number of organisms per kidney significantly compared with that in infected untreated controls within 48 h after the initiation of therapy. At 20 mg/kg given once a day, daptomycin is less effective but reduces colony counts significantly after 4 days of therapy, and its activity is comparable to that of vancomycin or vancomycin-gentamicin given twice daily.
相关产品:Natural Product Library Plus | Drug Repurposing Compound Library Plus | FDA-Approved Drug Library Plus | FDA-Approved Drug Library Mini | Bioactive Compound Library Plus | Anti-Infection Compound Library | Natural Product Library | FDA-Approved Drug Library | Anti-Cancer Compound Library | Peptidomimetic Library | Drug Repurposing Compound Library | Macrocyclic Compound Library | Antibacterial Compound Library | NMPA-Approved Drug Library | FDA Approved & Pharmacopeial Drug Library | Antibiotics Library | Drug-Induced Liver Injury (DILI) Compound Library | Microbial Metabolite Library | Children’s Drug Library | Peptide Library | Anti-Cancer Natural Product Library | Cyclic Peptide Library | EMA-Approved Drug Library | FDA-Approved Anticancer Drug Library | Off-patent Drug Library | Rapamycin | Cycloheximide | Chloroquine | Doxorubicin hydrochloride | Bafilomycin A1 | Dimethyl sulfoxide | Dexamethasone | Puromycin dihydrochloride | Staurosporine | Actinomycin D | G-418 disulfate | Etoposide | 5-Azacytidine | Cyclosporin A | Nigericin sodium salt | Brefeldin A | CCCP | Estradiol | Bleomycin sulfate | Hygromycin B | Ionomycin | Resveratrol | Mitomycin C | Tunicamycin | Everolimus | Tacrolimus | Doxycycline hyclate | Oligomycin
热门产品线:重组蛋白 | 药物筛选 | 天然产物 | 荧光染料 | PROTAC | 同位素标记物
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Dye Reagents | PROTAC | Isotope-Labeled Compounds
品牌介绍:
• MCE (MedChemExpress) 拥有200 多种全球独家化合物库,我们致力于为全球科研客户提供前沿最全的高品质小分子活性化合物;
• 50,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域;
• 产品种类涵盖各种重组蛋白,多肽,常用试剂盒 ,更有 PROTAC、ADC 等特色产品,广泛应用于新药研发、生命科学等科研项目;
• 提供虚拟筛选,离子通道筛选,代谢组学分析检测分析,药物筛选等专业技术服务;
• 设有专业的实验中心和严格的质控、验证体系;
• 提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告,确保产品的高纯度、高品质;
• 产品的生物活性多经各国客户实验验证;
• Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果;
• 专业团队跟踪最新的制药及生命科学研究进展,为您提供全球最新的活性化合物;
• 与世界各大制药公司及知名科研机构建立了长期的合作。
Daptomycin | 达托霉素 | MedChemExpress (MCE)信息由MedChemExpress (MCE)为您提供,如您想了解更多关于Daptomycin | 达托霉素 | MedChemExpress (MCE)报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途