Bradykinin (1-7) | MedChemExpress (MCE)

Bradykinin (1-7) 产品活性：Bradykinin (1-7) 是一种氨基截短的激肽肽。Bradykinin (1-7) 是由内肽酶切割形成的一种 Bradykinin 代谢物。 产品来源： https://www.medchemexpress.cn/Bradykinin_1-7.html 研究领域：GPCR/G Protein 作用靶点：Bradykinin Receptor In Vitro: The Bradykinin peptide system is a tissue-based system with potent cardiovascular and renal effects. To investigate the regulation of this system, a highly sensitive amino terminal-directed radioimmunoassay that, with high performance liquid chromatography, enables the measurement of Bradykinin-(1-7), Bradykinin-(1-8), and Bradykinin-(1-9), is developed. Together with a carboxy terminal-directed radioimmunoassay, Bradykinin peptides in rat kidney and blood are characterized. The predominant Bradykinin peptides in kidney are Bradykinin-(1-9) (~100 fmol/g wet weight of tissue) and Bradykinin-(1-7) (~70 fmol/g), with low levels of Bradykinin-(1-8) (~8 fmol/g) and Bradykinin-(4-9) (~12 fmol/g) detectable; Bradykinin-(2-9) and Bradykinin-(3-9) are below the limits of detection. In blood, the levels of Bradykinin-(1-9) are very low (~2 fmol/ml), and other Bradykinin peptides are below the limits ofdetection. Administration of the angiotensin converting enzyme (ACE) inhibitor Perindopril is associated with an approximate twofold increase in renal levels of Bradykinin-(1-8) and Bradykinin-(1-9) and a decrease in the Bradykinin-(1-7)/Bradykinin-(1-9) ratio. The amino terminal-directed radioimmunoassay is also applied to heart, aorta, brown adipose tissue, adrenal, lung, and brain. For these tissues, Bradykinin-(1-7) and Bradykinin-(1-9) are of similar abundance (16-340 fmol/g), with lower levels of Bradykinin-(1-8). 相关产品：Bioactive Compound Library Plus | GPCR/G Protein Compound Library | Anti-Cardiovascular Disease Compound Library | Endocrinology Compound Library | Neurotransmitter Receptor Compound Library | Peptide Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | Bioactive Compound Library Max | Bradykinin | Icatibant | [Des-Arg9]-Bradykinin acetate | SSR240612 | Lobradimil | Lys-[Des-Arg9]Bradykinin TFA | ELN-441958 | Fulimetibant | MEN 11270 | Bradykinin (2-9) | [Tyr8] Bradykinin | Bradykinin (1-5) | Bradykinin (1-6) | R715 | Sar-[D-Phe8]-des-Arg9-Bradykinin | B 9430 | Bombinakinin M | Des-Arg9-[Leu8]-Bradykinin acetate | Fasitibant chloride | FR173657 | Lys-(Des-Arg9,Leu8)-Bradykinin | Lys-Bradykinin | Lys-[Des-Arg9]Bradykinin | Lys-[Hyp3]-Bradykinin | Methionyl-Lysyl-Bradykinin 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。

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