Z-VDVAD-FMK | MedChemExpress (MCE)

Z-VDVAD-FMK 产品活性：Z-VDVAD-FMK 是一种特异性的 caspase-2 抑制剂。Z-VDVAD-FMK 可减少 Lovastatin 诱导的细胞凋亡 (apoptosis)。 产品来源： https://www.medchemexpress.cn/z-vdvad-fmk.html 研究领域：Apoptosis 作用靶点：Caspase In Vitro: Cotreatment of cells with the caspase inhibitors Ac-DEVD-CHO, Z-VDVAD-FMK (100 μM), Z-IETD-fmk, and Z-LEHD-fmk alone or in combination, or overexpression of CrmA, prevents many morphological features of apoptosis but not loss of mitochondrial membrane potential (DCm), phospatidilserine exposure, and cell death. Z-VDVAD-FMK (2 μM) greatly inhibits the Rho-kinase activity in HMEC-1 cells stimulated by Thrombin and displays no effect on control cells.  Z-VDVAD-FMK (zVDVAD-fmk) produces a reduction in Lovastatin-induced apoptosis. Z-VDVAD-FMK (100 μM) significantly reduces Lovastatin-induced loss of DNA by 19.1±8.3%. 相关产品：Bioactive Compound Library Plus | Apoptosis Compound Library | Anti-Cancer Compound Library | Peptide Library | Protease Inhibitor Library | Membrane Protein-targeted Compound Library | Highly Selective Inhibitors Library | Bioactive Compound Library Max | Z-VAD-FMK | Q-VD-OPh | Belnacasan | Sulforaphane | Z-DEVD-FMK | Emricasan | Tauroursodeoxycholate | Aspirin | Z-IETD-FMK | Ac-YVAD-cmk | Oxidopamine hydrobromide | Ac-DEVD-CHO | Raptinal | Chlorin e6 | Crustecdysone | Guggulsterone | Wedelolactone | Benzbromarone | Ac-FLTD-CMK | BOC-D-FMK | Fucoxanthin | Ginsenoside Rh2 | Dehydrocorydaline | VRT-043198 | Terfenadine | Digitoxin | PAC-1 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。

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