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Peptide 401 | MedChemExpress (MCE)

英文名称:Peptide 401
品牌 厂商性质 产地 货期 价格
MedChemExpress (MCE) 生产商 美国 现货 1350

性能特点

Peptide 401 是一种有效的来源于蜂毒中的肥大细胞脱颗粒肽,抑制血管通透性。

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产品参数
规格 CAS号 价格 操作
500 μg 32908-73-9 ¥1,350.00 询底价
产品介绍

Peptide 401 产品活性:Peptide 401 是一种有效的来源于蜂毒中的肥大细胞脱颗粒肽,抑制血管通透性。 产品来源: https://www.medchemexpress.cn/Peptide_401.html 研究领域:GPCR/G Protein | Neuronal Signaling | Immunology/Inflammation 作用靶点:Histamine Receptor | 5-HT Receptor In Vivo: Peptide 401 substantially inhibits the oedema provoked by subplantar injection of carrageenin or intra-articular injection of turpentine in the rat. The ED50 of 401 is c. 0.1 mg/kg. The anti-inflammatory effect is assessed by measurement of the increased 125I-albumin content of an injected site in comparison with an uninjected contralateral site. Peptide 401 also suppresses the increased vascular permeability due to intradermal injection of various smooth muscle spasmogens (histamine, bradykinin, 5-hydroxytryptamine (5-HT), and prostaglandins). Peptide 401 (MCD peptide) contains 22 residues and occurs in the venom of the common European honey bee to the extent of about 2% by weight . It has powerful anti-inflammatory activity (at doses as low as 0.1 mg/kg) in a variety of animal models, i.e., hind paw oedema in the rat induced by carrageenin or turpentine, adjuvant arthritis in the rat, and increased skin permeability in the rat resulting from subcutaneous injection of bradykinin, prostaglandin E1 kallikrein, histamine and 5- hydroxytryptamine (5-HT). It has a powerful degranulating effect on mast cells and involves the release of histamine and other pharmacologically active agents. 相关产品:Bioactive Compound Library Plus | Peptide Library | Histamine | Chlorpromazine hydrochloride | Serotonin hydrochloride | SCH-23390 hydrochloride | Harmine | Puerarin | PNU-282987 | Clemastine fumarate | Scopolamine hydrobromide | Clozapine | Risperidone | Vortioxetine | Olanzapine | Dihydroergotamine mesylate | Aripiprazole | Astemizole | Cimetidine | GTS-21 dihydrochloride | Terfenadine | Amitriptyline hydrochloride | Loratadine | Ondansetron | Mecamylamine hydrochloride | Thioridazine hydrochloride | Brexpiprazole | SB-269970 hydrochloride | Cisapride 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物,我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物;10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域;设有专业的实验中心和严格的质控、验证体系;提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告,确保产品的高纯度、高品质;产品的生物活性多经各国客户实验验证;Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果;专业团队跟踪最新的制药及生命科学研究进展,为您提供全球最新的活性化合物;与世界各大制药公司及知名科研机构建立了长期的合作。

Peptide 401 | MedChemExpress (MCE)信息由MedChemExpress (MCE)为您提供,如您想了解更多关于Peptide 401 | MedChemExpress (MCE)报价、型号、参数等信息,欢迎来电或留言咨询。

注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途

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