Deltarasin | MedChemExpress (MCE)

Deltarasin 产品活性：Deltarasin 是一种 KRAS-PDEδ 相互作用的抑制剂，能够与 PDEδ 结合，Kd 值为 38 nM。 产品来源： https://www.medchemexpress.cn/Deltarasin.html 研究领域：GPCR/G Protein | MAPK/ERK Pathway | Metabolic Enzyme/Protease 作用靶点：Ras | Phosphodiesterase (PDE) In Vitro: In liver cells, deltarasin inhibits the interaction of RAS with PDEδ with Kd of 41 nM. Inhibition of PDEδ-KRAS interaction by deltarasin suppresses proliferation of human pancreatic ductal adenocarcinoma cells that are dependent on oncogenic KRAS. In Vivo: Deltarasin (10 mg/kg, i.p.) impairs dose-dependent tumor growth in nude mice bearing subcutaneous human Panc-Tu-I tumour cell xenografts. 相关产品：Bioactive Compound Library Plus | GPCR/G Protein Compound Library | Immunology/Inflammation Compound Library | Kinase Inhibitor Library | MAPK Compound Library | Metabolism/Protease Compound Library | Anti-Cancer Compound Library | Oxygen Sensing Compound Library | Ferroptosis Compound Library | Glutamine Metabolism Compound Library | Anti-Alzheimer's Disease Compound Library | Anti-Pancreatic Cancer Compound Library | Anti-Blood Cancer Compound Library | Neurodegenerative Disease-related Compound Library | Angiogenesis-Related Compound Library | Anti-Liver Cancer Compound Library | Anti-Colorectal Cancer Compound Library | Protein-protein Interaction Inhibitor Library | Metabolic Enzyme Compound Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | Anti-Hematopathy Compound Library | Multi-Target Compound Library | Bioactive Compound Library Max | IBMX | Sotorasib | MRTX1133 | Adagrasib | Bucladesine sodium | BI-2865 | BI-2852 | BI-3406 | Ketoconazole | Rolipram | NSC 23766 trihydrochloride | Roflumilast | Sildenafil | Apremilast | Icariin | Theophylline | Dipyridamole | Milrinone | RMC-6236 | Rhosin hydrochloride | CID-1067700 | GGTI298 Trifluoroacetate | ML141 | Divarasib | Lonafarnib | EHT 1864 | BAY-293 | RMC-7977 | MBQ-167 | MRTX0902 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途