7-Chlorokynurenic acid sodium salt | MedChemExpress (MCE)

7-Chlorokynurenic acid sodium salt 产品活性：7-Chlorokynurenic acid sodium salt (7-CKA sodium salt) 是一种有效且选择性的 N-methyl-D-aspartate (NMDA) 受体的甘氨酸 B 激动剂位点拮抗剂 (IC50=0.56 μM)。7-Chlorokynurenic acid sodium salt 也是谷氨酸重摄取到突触小泡中的有效抑制剂，Ki 为 0.59 μM。7-Chlorokynurenic acid sodium salt 可用于缓解疼痛的研究。 产品来源： https://www.medchemexpress.cn/7-Chlorokynurenic_acid_sodium_salt.html 研究领域：Membrane Transporter/Ion Channel | Neuronal Signaling 作用靶点：iGluR In Vivo: Male Sprague-Dawley rats pretreated with 7-Chlorokynurenic acid sodium salt (10 nM) shows a significant retardation of development of both the electroencephalographic and motor (17.7±2.9 daily stimulations) components of the seizure response. 相关产品：Bioactive Compound Library Plus | Membrane Transporter/Ion Channel Compound Library | Neuronal Signaling Compound Library | Neurotransmitter Receptor Compound Library | Anti-Alzheimer's Disease Compound Library | Neuroprotective Compound Library | Anti-Parkinson's Disease Compound Library | Neurodegenerative Disease-related Compound Library | Antidepressant Compound Library | Human Metabolite Library | Heterocyclic Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | Highly Selective Inhibitors Library | Ion Channel Compound Library | Bioactive Compound Library Max | Corticosterone | Dizocilpine maleate | D-AP5 | NMDA | L-Glutamic acid | Evans Blue | CNQX | Kynurenic acid | Glycine | L-Phenylalanine | NBQX | Quinolinic acid | Cycloleucine | Ifenprodil tartrate | Memantine hydrochloride | D-Cycloserine | DNQX | Ro 25-6981 Maleate | (-)-Huperzine A | Naspm trihydrochloride | Ibotenic acid | 24-Hydroxycholesterol | Crocetin | Decanoic acid | Bupivacaine | Topiramate | Tacrine hydrochloride 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。

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