CHPG sodium salt | MedChemExpress (MCE)

CHPG sodium salt 产品活性：CHPG sodium salt 是一个选择性的 mGluR5 激动剂，并且通过 TSG-6/NF-κB 途径减弱 BV2 小神经胶质细胞 SO2 诱导的氧化应激和炎症。 CHPG sodium salt 通过 ERK 和 Akt 途径在体外和体内预防创伤性脑损伤 (TBI)。 产品来源： https://www.medchemexpress.cn/chpg-sodium-salt.html 研究领域：GPCR/G Protein | Neuronal Signaling | NF-κB | Stem Cell/Wnt | MAPK/ERK Pathway | PI3K/Akt/mTOR 作用靶点：mGluR | NF-κB | ERK | Akt In Vitro: CHPG sodium salt (10-500?μM; 24?hours) significantly increases the cell viability and decreases the LDH release after SO2 derivatives treatment. ? CHPG sodium salt (0.5?mM; 30?mins ) protects BV2 cells against SO2-induced apoptosis. ? CHPG sodium salt (0.5 mM; 30?mins) treatment alone increases the expression of TSG-6 in both mRNA and protein levels. In Vivo: CHPG sodium salt (injection; 250 nM; for 7 days) reduces significantly cerebral lesion volume. 相关产品：Bioactive Compound Library Plus | GPCR/G Protein Compound Library | Immunology/Inflammation Compound Library | MAPK Compound Library | Neuronal Signaling Compound Library | NF-κB Signaling Compound Library | PI3K/Akt/mTOR Compound Library | Stem Cell Signaling Compound Library | Autophagy Compound Library | Anti-Aging Compound Library | Antioxidant Compound Library | Oxygen Sensing Compound Library | Glycolysis Compound Library | Pyroptosis Compound Library | Cytoskeleton Compound Library | Neurotransmitter Receptor Compound Library | Glutamine Metabolism Compound Library | Neuroprotective Compound Library | Anti-Pancreatic Cancer Compound Library | Anti-Cancer Metabolism Compound Library | Anti-Parkinson's Disease Compound Library | Neurodegenerative Disease-related Compound Library | Angiogenesis-Related Compound Library | Transcription Factor-Targeted Library | Glucose Metabolism Compound Library | Targeted Diversity Library | Antidepressant Compound Library | Human Metabolite Library | Osteogenesis Compound Library | Pain-Related Compound Library | Mitochondrial Protection Compound Library | Membrane Protein-targeted Compound Library | Membrane Receptor-targeted Compound Library | Highly Selective Activators Library | Multi-Target Compound Library | Radioprotector Library | Bioactive Compound Library Max | Phorbol 12-myristate 13-acetate | Bortezomib | Deferoxamine mesylate | MK-2206 dihydrochloride | BAY 11-7082 | PD98059 | SC79 | Yoda 1 | Capivasertib | TAK-243 | Afatinib | JSH-23 | SCH772984 | TBHQ | Shikonin | Tauroursodeoxycholate | Sulfasalazine | Triptolide | Ipatasertib | Aspirin | Pyrrolidinedithiocarbamate ammonium | Baicalin | Dihydroartemisinin | L-Glutamine | Chloramphenicol | Ulixertinib | Honokiol | β-Glycerophosphate disodium salt pentahydrate | 5-Aminosalicylic Acid | Astragaloside IV 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途