MCT1-IN-3 | MedChemExpress (MCE)

MCT1-IN-3 产品活性：MCT1-IN-3 是一种单羧酸转运蛋白 1 (MCT1) 抑制剂，IC50 值为 81.0 nM。MCT1-IN-3 还对多药转运蛋白 ABCB1 具有显著的抑制作用。MCT1-IN-3 可用于癌症的研究。 产品来源： https://www.medchemexpress.cn/mct1-in-3.html 研究领域：Membrane Transporter/Ion Channel 作用靶点：Monocarboxylate Transporter | P-glycoprotein In Vitro: MCT1-IN-3 (compound 24) has inhibitory activity for MCT1 with an IC50 value of 81.0 nM. MCT1-IN-3 has great antiproliferative activities against the MCT1-expressing cancer cell lines A-549 and MCF-7 with GI50 values of 20 μM and 15.1 μM, respectively. MCT1-IN-3 (5 μM; 24 h) leads to cancer cell cycle arrest as well as apoptosis. MCT1-IN-3 (1.0, 2.0, 3.5, and 5.0 μM) shows to sensitize these cancer cells toward an antineoplastic agent. MCT1-IN-3 has also significant inhibitory power against the multidrug transporter ABCB1 and shows to reverse ABCB1-mediated multidrug resistance (MDR) . 相关产品：AZD3965 | Verapamil | Elacridar | AR-C155858 | Tariquidar | Glibenclamide | Syrosingopine | VB124 | Zosuquidar trihydrochloride | Piperine | Risperidone | AZD0095 | α-Cyano-4-hydroxycinnamic acid | CP-100356 hydrochloride | Limonin | Trifluoperazine dihydrochloride | BAY-8002 | Valspodar | 7ACC2 | MSC-4381 | Paris saponin VII | 7ACC1 | Atazanavir sulfate | Silychristin | Solamargine | Encequidar | Dofequidar fumarate 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。

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