Abemaciclib metabolite M18-d8 产品活性：Abemaciclib metabolite M18-d8 是 Abemaciclib metabolite M18 的氘代物。Abemaciclib metabolite M18 (LSN3106729)，Abemaciclib 的代谢物， 是一种具有抗肿瘤活性的 CDK 抑制剂。Abemaciclib metabolite M18 和 CRBN 配体可用于设计 PROTAC CDK4/6 降解剂。 产品来源： https://www.medchemexpress.cn/abemaciclib-metabolite-m18-d8.html 研究领域：Cell Cycle/DNA Damage | PROTAC 作用靶点：CDK | Ligands for Target Protein for PROTAC In Vitro: Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs. 相关产品：Palbociclib | (+)-JQ-1 | Ibrutinib | Abemaciclib | Ro-3306 | Ribociclib | Dinaciclib | GSK3326595 | Quizartinib | Flavopiridol | (R)-Roscovitine | THZ1 | AZD4573 | THZ531 | SR-4835 | Kenpaullone | SY-5609 | Wogonin | GSK 3 Inhibitor IX | SNS-032 | Toyocamycin | Cirtuvivint | NVP-2 | Simurosertib | OTS964 hydrochloride | AT7519 | PF-07220060 品牌介绍: MCE (MedChemExpress) 拥有数百种全球独家化合物，我们致力于为全球科研客户提供最新最全的高品质小分子活性化合物；10,000 多种高选择性抑制剂、激动剂涉及各热门信号通路及疾病领域；设有专业的实验中心和严格的质控、验证体系；提供 LC/MS、NMR、HPLC、手性分析、元素分析等各项质检报告，确保产品的高纯度、高品质；产品的生物活性多经各国客户实验验证；Nature, Cell, Science 等多种顶级期刊及制药专利收录了MCE客户的科研成果；专业团队跟踪最新的制药及生命科学研究进展，为您提供全球最新的活性化合物；与世界各大制药公司及知名科研机构建立了长期的合作。