醋酸可的松 T0034
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mL | 50-04-4 | ¥210.00 | 询底价 |
1 g | 50-04-4 | ¥198.00 | 询底价 |
500 mg | 50-04-4 | ¥148.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Cortisone acetate
描述: Cortisone acetate (NSC-49420) 是 Cortisol(一种糖皮质激素)的氧化代谢产物。它在高浓度下能够部分干预 Glucocorticoid 与Glucocorticoid-receptor 的结合。它具有免疫抑制和消炎的作用。
激酶实验: Levels of enzymatically active caspase-3 are quantified using the ApoAlert Caspase Fluorescent assay kit. Briefly, 1×106 BC-1 PEL cells are treated with 50 μM Miltefosine, 50 μM Perifosine, or 20 nM NVP-BEZ235, as well as the respective vehicle controls. Cells are harvested and lysed 12 hours later. Equivalent micrograms of cell lysate for all samples are incubated with a fluorogenic caspase-3 substrate (DEVD-AFC). Cleavage of DEVD by caspase-3 releases AFC, the fluorescence of which is measured using a FLUOstar OPTIMA fluorometer, with excitation and emission filter wavelengths set to 400 and 505 nm, respectively[3].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 7 mg/mL (17.39 mM)
Ethanol : < 1 mg/mL (insoluble or slightly soluble)
关键字: Cortisone | Cortisone acetate | immunosuppressant | Glucocorticoid Receptor | Endogenous Metabolite | inhibit | Cortisone Acetate | anti-inflammatory | NSC49420 | NSC-49420 | Inhibitor
相关产品: Beclometasone | AZD9567 | Osilodrostat | Vamorolone | Fluorometholone | Methylprednisolone succinate | Fluticasone furoate | Megestrol acetate | TPI-1 | AZD5423
相关库: Human Endogenous Metabolite Library | Drug Repurposing Compound Library | ReFRAME Related Library | Anti-Cancer Drug Library | Anti-Cancer Clinical Compound Library | Inhibitor Library | Nuclear Receptor Compound Library | Anti-Cancer Approved Drug Library | Endocrinology-Hormone Compound Library | RO5 Drug-like Natural Product Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途