可可碱 T0625

Product Introduction
Bioactivity


英文名: Theobromine

描述: Theobromine (3,7-Dimethylxanthine) 是在可可豆中发现的一种甲基黄嘌呤，抑制腺苷受体 A1 信号传导，用作支气管扩张剂和血管扩张剂。

体外活性: Theobromine (3,7-二甲基黄嘌呤)是一种黄嘌呤类生物碱，用作支气管扩张剂和血管扩张剂。[1] Theobromine利尿作用较茶碱弱，且对平滑肌的兴奋作用也较弱。[2] 与咖啡因不同，Theobromine对中央神经系统几乎无刺激效果，但可能通过周围生理改变提升情绪和认知功能。[3] Theobromine 曾用作利尿剂及治疗心绞痛和高血压的化合物。[4]

体内活性: LD50: 兔 >200 mg/kg（经口）[5]

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 1mg/ml


关键字: Adenosine Receptor | P1 receptor | Theobromine | Endogenous Metabolite | Inhibitor | inhibit

相关产品: Tricosanoic acid | 2,6-Dimethoxybenzoic acid | N2-methylguanine | 2-Phenylbutanoic acid | Uridine triphosphate | 2'-Deoxyadenosine | 2-Deoxy-2-sulfoamino-D-glucose sodium | 1-Aminocyclopropane-1-carboxylic acid | Tricaprin | Catechin

相关库: Drug Repurposing Compound Library | Anti-Neurodegenerative Disease Compound Library | Bioactive Lipid Compound Library | Tobacco Monomer Library | Anti-Cancer Drug Library | Membrane Protein-targeted Compound Library | Anti-Cancer Clinical Compound Library | GPCR Compound Library | Traditional Chinese Medicine Monomer Library | Anti-Cancer Approved Drug Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途