熊去氧胆酸 T0700

Product Introduction
Bioactivity


英文名: Ursodeoxycholic acid

描述: Ursodeoxycholic acid (UDCA) 是一种有效的肝脏特异性脂肪酸转运蛋白 5 (FATP5) 抑制剂，通过 FATP5 依赖性方式抑制原代肝细胞摄取长链脂肪酸。Ursodeoxycholic acid 能够抑制胆固醇的吸收，用于溶解胆结石，并具有研究与肥胖相关的脂肪肝疾病的潜力。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: Ethanol : 73 mg/mL (186 mM)
DMSO : 55 mg/mL (140.1 mM)
5% DMSO+95% Saline : 3.65 mg/mL (9.3 mM, suspension)
H2O : < 1 mg/mL (insoluble or slightly soluble)


关键字: inhibit | intestinal barrier integrity | oral | FXR | G-protein coupled receptor 19 | G protein-coupled Bile Acid Receptor 1 | Endogenous Metabolite | Inhibitor | GPBAR1 | Ursodeoxycholic acid | hepatic | GPCR19 | TGR5 | secondary bile acid | gastrointestinal diseases | NR1H4 | Ursodeoxycholate | lipid metabolism

相关产品: KTX-Sp2 | Cesium chloride | Ssm spooky toxin | Dihydroberberine | NS19504 | Senicapoc | ICA 110381 | ML277 | Spinoxin | Flindokalner

相关库: Drug Repurposing Compound Library | Human Endogenous Metabolite Library | Anti-Inflammatory Traditional Chinese Medicine Compound Library | Anti-Cancer Drug Library | Membrane Protein-targeted Compound Library | Inhibitor Library | Anti-Cancer Clinical Compound Library | Anti-virus Traditional Chinese Medicine Monomer Library | Anti-Cancer Approved Drug Library | Traditional Chinese Medicine Monomer Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途