芬布芬 T0859
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 mg | 36330-85-5 | ¥298.00 | 询底价 |
100 mg | 36330-85-5 | ¥418.00 | 询底价 |
1 mL | 36330-85-5 | ¥460.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Fenbufen
描述: Fenbufen (Lederfen) 是一种非甾体抗炎药,主要用于治疗骨关节炎、强直性脊柱炎和肌腱炎的炎症。它还可用于缓解背痛、扭伤和骨折,具有 caspases 的抑制活性。它对 COX-1和 COX-2具有抑制活性,其 IC50分别为 3.9 μM 和 8.1 μM。
体内活性: Fenbufen and its metabolites could be involved in mitochondrial toxicity through inhibition of ATP synthesis[1]. Fenbufen inhibited prostaglandin release by 80% and reduced rates of protein synthesis in normal muscle and in muscle undergoing hypertrophy in response to tenotomy of a synergist[3].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: Ethanol : 47 mg/mL (184.8 mM)
DMSO : 47 mg/mL (184.8 mM)
H2O : < 1 mg/mL (insoluble or slightly soluble)
关键字: anti-inflammatory | tendinitis | analgetic | Caspase | COX | Inhibitor | inhibit | CL 82204 | antipyretic | ankylosing spondylitis | antirheumatic | osteoarthritis | CL82204 | Cyclooxygenase | Fenbufen
相关产品: Chlorpropamide | Lasiodiplodin | Leminoprazole | Suloctidil | SCH28080 | Ciclopirox | Sodium oleate | Digitoxin | D-α-Hydroxyglutaric acid disodium | Brefeldin A
相关库: Drug Repurposing Compound Library | Pyroptosis Compound Library | Drug-Fragment Library | FDA-Approved & Pharmacopeia Drug Library | Mitochondria-Targeted Compound Library | Anti-Cancer Drug Library | Membrane Protein-targeted Compound Library | Neuronal Signaling Compound Library | Inhibitor Library | Anti-Cancer Approved Drug Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途