化合物AR antagonist 1 T10359

Product Introduction
Bioactivity


英文名: AR antagonist 1

描述: AR antagonist 1 是 AR 拮抗剂，能够与 E3 连接酶配体结合，与 VHL 蛋白结合亲和力较弱，用于 PROTACARD-266 合成。

体外活性: AR antagonist 1 是ARD-266靶向连接酶的配体。ARD-266是一种基于VHL E3连接酶的高效雄激素受体（AR）PROTAC降解剂。AR antagonist 1 对其E3连接酶复合物表现出微摩尔级的结合亲和力，因此它可以有效用于设计高效的PROTAC降解剂。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 60 mg/mL (215.22 mM)


关键字: AR antagonist1 | Target Protein-binding Moiety | AR antagonist-1 | Inhibitor | AR antagonist 1 | LNCaP | Linker | Ligands for Target Protein for PROTAC | inhibit | cancer | Ligands for E3 Ligase | VCaP | PROTAC | tumor | E3 ligase-recruiting Moiety

相关产品: SMER3 | (S,R,S)-AHPC-PEG1-N3 | TL12-186 | Thalidomide 5-fluoride | E3 ligase Ligand 23 | VH032-cyclopropane-F | (S,R,S)-AHPC-C4-NH2 hydrochloride | MS4078 | Thalidomide-O-amido-PEG3-C2-NH2 TFA | Lenalidomide-Br

相关库: Anti-Prostate Cancer Compound Library | Transcription Factor-Targeted Compound Library | Anti-Cancer Compound Library | Bioactive Compounds Library Max | Nuclear Receptor Compound Library | Endocrinology-Hormone Compound Library | NO PAINS Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途