化合物BMS-1001 hydrochloride T10565

Product Introduction
Bioactivity


英文名: BMS-1001 hydrochloride

描述: BMS-1001 hydrochloride 是一种人 PD-L1/PD-1免疫检查点的抑制剂，具有口服活性且细胞毒性低。

体外活性: BMS-1001与人体PD-L1结合，并阻断其与PD-1的相互作用。BMS-1001缓解了可溶性PD-L1对T细胞受体介导的T淋巴细胞激活的抑制效应。它对所测试的细胞系的毒性低，抑制可溶性PD-L1与细胞表面表达的PD-1的交互作用。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 11.5 mg/mL(18.22 mM)


关键字: Inhibitor | BMS 1001 | BMS-1001 Hydrochloride | inhibit | ICB | toxicity | BMS1001 | immune | checkpoint | BMS1001 Hydrochloride | BMS 1001 hydrochloride | BMS 1001 Hydrochloride | BMS-1001 | BMS1001 hydrochloride | low

相关产品: Acrixolimab | PD-1/PD-L1-IN-32 | BMS-1001 | Danburstotug | SWS1 | PD-1/PD-L1-IN-34 | PD-1-IN-17 | PD-L1-IN-3 | LSD1-IN-27 | BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride

相关库: Anti-Liver Cancer Compound Library | Anti-Breast Cancer Compound Library | Anti-Cancer Compound Library | Immuno-Oncology Compound Library | Bioactive Compounds Library Max | Inhibitor Library | PPI Inhibitor Library | Orally Active Compound Library | NO PAINS Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途