化合物F-1 T11254

Product Introduction
Bioactivity


英文名: F-1

描述: F-1 是 ALK 和 ROS1 的双重抑制剂，抑制 ALK 的磷酸化及下游通路，可作用于对 ALKWT (IC50:2.1 nM)，ROS1WT (IC50:2.3 nM)，ALKL1196M (IC50:1.3 nM) 和 ALKG1202R (IC50:3.9 nM)。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 100 mg/mL (192.67 mM)


关键字: F-1 | ALK tyrosine kinase receptor | CD246 | F 1 | Anaplastic lymphoma kinase (ALK) | Anaplastic lymphoma kinase | Inhibitor | F1 | ROS Kinase | Cluster of differentiation 246 | inhibit

相关产品: APG-2449 | ROS kinases-IN-2 | HS-291 | ROS kinases-IN-1 | Methyl 12-methyltridecanoate | Entrectinib | Salvigenin | Taletrectinib free base | Lorlatinib | Taletrectinib

相关库: Angiogenesis related Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Anti-Lung Cancer Compound Library | Kinase Inhibitor Library | Inhibitor Library | Tyrosine Kinase Inhibitor Library | Anti-Fibrosis Compound Library | Cuproptosis Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途