化合物 T11698 T11698
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
100 mg | 2223019-53-0 | ¥17,500.00 | 询底价 |
25 mg | 2223019-53-0 | ¥10,600.00 | 询底价 |
50 mg | 2223019-53-0 | ¥13,800.00 | 询底价 |
Product Introduction
Bioactivity
英文名: IZCZ-3
描述: IZCZ-3,antitumor activity. is a potent c-MYC transcription inhibitor.
体外活性: IZCZ-3 induces only weak growth inhibition in the BJ fibroblasts (IC50=15.9 μM) and mouse mesangial cells (IC50=15.6 μM), suggesting that IZCZ-3 is more effective against cancer cells than against c-MYC-independent normal cells. IZCZ-3 (0-5 μM; 12 hours) induces an apparent accumulation of cells in the G0/G1 phase in SiHa cells in a dose-dependent manner.IZCZ-3 (2.1 μM-15.9 μM; 24 hours) significantly inhibits SiHa, HeLa, Huh7, and A375 cancer cell proliferation (IC50s of 3.3, 2.1,4.1, and 4.2 μM, respectively).
体内活性: IZCZ-3 inhibits tumor growth in BALB/c nude mice with SiHa human cervical squamous cancer xenograft.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 5 mg/mL (6.98 mM)
关键字: IZCZ3 | IZCZ-3 | IZCZ 3
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途