化合物K-Ras G12C-IN-4 T11738

Product Introduction
Bioactivity


英文名: K-Ras G12C-IN-4

描述: K-Ras G12C-IN-4 是一种 KRAS G12C 共价抑制剂。

体外活性: K-Ras G12C-IN-4在4小时内给予抑制MIA PaCa-2细胞的MAPK信号转导路径（p-ERK），IC50值为0.219 μM[1]。在对MIA PaCa-2细胞进行72小时的CellTiter-Glo活性测试中，K-Ras G12C-IN-4可抑制其细胞活性，IC50为0.067 μM[1]。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 50 mg/mL (89.115 mM)


关键字: Inhibitor | K Ras G12C IN 4 | inhibit | K-Ras G12C-IN-4 | Ras | K-Ras G-12C-IN-4 | KRas G12CIN4

相关产品: CCG-100602 | KRAS G12C inhibitor 17 | KRAS G12C inhibitor 59 | KRAS G12D modulator-1 | Rhosin hydrochloride | CCG-222740 | KRAS G12C inhibitor 32 | HJC0197 | PROTAC K-Ras Degrader-1 | BI-2865

相关库: Anti-Prostate Cancer Compound Library | Anti-Cancer Metabolism Compound Library | Anti-Cancer Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Anti-Ovarian Cancer Compound Library | GPCR Compound Library | Kinase Inhibitor Library | Inhibitor Library | Reprogramming Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途