奥贝胆酸杂质9 T13092

Product Introduction
Bioactivity


英文名: Tauro-Obeticholic acid

描述: Tauro-Obeticholic acid 是一种牛磺酸的特性代谢物。Obeticholic Acid 是口服具有活性的法尼样 X 受体激动剂。

体外活性: 肝脏将Obeticholic acid和taurine结合形成taurine-obeticholic acid，然后该化合物被分泌至胆汁中。伊雷和结肠内的微生物能够分解taurine-obeticholic acid，并将其还原成母化合物，随后该化合物可以被重新吸收或通过粪便排出。

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 50 mg/mL (94.74 mM)


关键字: microorganisms | FXR | colon | Tauro-Obeticholic acid | NR1H4 | TauroObeticholic acid | inhibit | ileum | Inhibitor | Tauro Obeticholic acid | metabolite，liver

相关产品: Hyodeoxycholic acid | BAR502 | GSK2324 | LY367385 | Ursodeoxycholic acid sodium | ZLY28 | Chenodeoxycholic acid | Tropifexor | Cilofexor | GW 4064

相关库: Bioactive Compounds Library Max | Anti-Metabolism Disease Compound Library | Nuclear Receptor Compound Library | Natural Product Library for HTS | Lipid Metabolism Compound Library | Metabolism Compound Library | NO PAINS Compound Library | Natural Product Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途