化合物5α-Pregnane-3β,6α-diol-20-one T13518

Product Introduction
Bioactivity


英文名: 5α-Pregnane-3β,6α-diol-20-one

描述: 5α-Pregnane-3β,6α-diol-20-one 是促进有丝分裂的 progesterone 代谢物，可于血清不足时雄性激素反应的前列腺素癌细胞中产生。

体外活性: Progesterone is converted to 5α-pregnane-3β,6α-diol-20-one in human fibroblasts [1]. Pregnenolone and progesterone are avidly metabolized to 5α-pregnan-3β,6α-diol-20-one in the C4.2 cell line, with nearly complete conversions at 24 h and 18 h, respectively. Preferential 5α-pregnan-3β,6α-diol-20-one formation from early steroid precursors is independent of CYP17A1 but rather dependent on 3β-HSD activity [2].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 100 mg/mL (298.96 mM)


关键字: 5αPregnane3β,6αdiol20one | 5α Pregnane 3β,6α diol 20 one | 5a-Pregnane-3b,6a-diol-20-one | 5α-Pregnane-3β,6α-diol-20-one | inhibit | Inhibitor | 5alpha-Pregnane-3beta,6alpha-diol-20-one

相关库: Anti-Prostate Cancer Compound Library | Anti-Cancer Compound Library | Bioactive Compounds Library Max | Anti-Cancer Active Compound Library | Natural Product Library for HTS | RO5 Drug-like Natural Product Library | NO PAINS Compound Library | Covalent Inhibitor Library | Natural Product Library | Bioactive Compound Library

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