(S,S,S)-AHPC盐酸盐 T13877

Product Introduction
Bioactivity


英文名: (S,S,S)-AHPC hydrochloride

描述: (S,S,S)-AHPC hydrochloride ((S,S,S)-VH032-NH2 hydrochloride) 是 von Hippel-Lindau (VHL) 氨基砌块。(S,S,S)-AHPC (Compound 27) 常作为 (S,R,S)-AHPC 的阴性对照。(S,R,S)-AHPC 是基于 VH032 的 VHL 配体，可用于募集 VHL 蛋白。

体外活性: VHL is one of the most popular E3 ligases being recruited by bifunctional Proteolysis-targeting chimeras (PROTACs) to induce ubiquitination and subsequent proteasomal degradation of a target protein.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: H2O : 99 mg/mL (211.98 mM)
DMSO : 60 mg/mL (128.47 mM)


关键字: VH032-NH2 Hydrochloride | Ligands for E3 Ligase | (S,S,S)AHPC hydrochloride | (S,S,S)-AHPC | Inhibitor | AHPC Hydrochloride | inhibit | (S,S,S) AHPC hydrochloride | E3 ligase-recruiting Moiety

相关产品: Thalidomide 5-fluoride | Pomalidomide-C2-NH2 | Pomalidomide-PEG4-Ph-NH2 | (S,R,S)-AHPC-PEG2-N3 | Thalidomide-5-OH | Thalidomide-O-amido-C4-N3 | VH032 | Thalidomide-NH-C4-NH-Boc | Lenalidomide-OH | Pomalidomide

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途