化合物 T14328 T14328
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 1214726-89-2 | ¥20,500.00 | 询底价 |
100 mg | 1214726-89-2 | ¥35,500.00 | 询底价 |
50 mg | 1214726-89-2 | ¥27,300.00 | 询底价 |
Product Introduction
Bioactivity
英文名: AS2521780
描述: AS2521780 is an inhibitor of PKCθ (IC50: 0.48 nM).
体外活性: AS2521780 suppresses CD3/CD28-induced Interleukin-2 (IL-2) gene transcription in Jurkat T cells and proliferation of human primary T cells and it also suppresses concanavalin A-induced cytokine production by rat splenocytes and monkey peripheral blood mononuclear cells with similar potency[1]. AS2521780 exerts potent inhibition of recombinant human PKCθ enzyme activity (IC50=0.48 nM). Which is more than 30-fold higher than that of other PKC isoforms. Further, AS2521780 exerts little or no inhibition on other protein kinases.
体内活性: AS2521780 significantly reduces paw swelling in a dose-dependent manner in a rat model of adjuvant-induced arthritis[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: AS2521780 | AS 2521780 | AS-2521780
相关产品: PD168393 | Chelerythrine | Syk Inhibitor II dihydrochloride | K-252c | Bisindolylmaleimide V | PKCα (C2-4) inhibitor peptide | Pinoresinol dimethyl ether | [Ala113]-MBP (104-118) acetate | SU9516 | 1,2-Dimyristoyl-sn-glycerol
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途