阿昔洛韦 T1454
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 mg | 59277-89-3 | ¥460.00 | 询底价 |
100 mg | 59277-89-3 | ¥739.00 | 询底价 |
1 mL | 59277-89-3 | ¥385.00 | 询底价 |
25 mg | 59277-89-3 | ¥277.00 | 询底价 |
500 mg | 59277-89-3 | ¥1,263.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Acyclovir
描述: Acyclovir (Aciclovir) 是鸟嘌呤类似物和具有口服活性的抗病毒剂。它对HSV-1(IC50为 0.85 μM),HSV-2(IC50为 0.86 μM) 和水痘带状疱疹病毒有活性。
激酶实验: Total AMPK activity is measured using the method of Dagher et al. AMPK activity is quantified in the resuspended pellet as incorporation of?32P from [γ-32P]ATP (10 GBq/mmol) into a synthetic peptide with the specific target sequence for AMPK, the SAMS peptide. Radioactivity is measured using a liquid scintillation counter. Protein content in the solution containing the resupended (NH4)2SO4 pellet is determined using the Bradford method.
体外活性: Acyclovir sensitivity of herpes simplex virus isolates is determined in a plaque-reduction assay in Vero cells. IC50 Values are consistently 2-3 fold lower in B2 compared with the H strain of Vero cells. HSV Type 2 strains are 2-10-fold less sensitive than Type 1 strains[2].
体内活性: low-dose oral acyclovir may be effective in the prevention of HSV infection during OKT3 treatment of seropositive patients. Continuation of acyclovir prophylaxis for two to four weeks following the conclusion of OKT3 therapy may prevent occurrence of delayed infections[3].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 55 mg/mL (244.23 mM)
Ethanol : < 1 mg/mL (insoluble or slightly soluble)
关键字: inhibit | Inhibitor | Herpes simplex virus | thymidine | triphosphate | HSV | immunosuppression | DNA | Antibiotic | Acyclovir | anti-herpetic | Apoptosis | kinase | antibody | polymerase | Bacterial
相关产品: Pantoprazole | β-Elemonic Acid | Notopterol | GSK2656157 | Mangiferin | CITCO | Ginkgetin | A09-003 | Unesbulin | EI1
相关库: Anti-Aging Compound Library | Drug Repurposing Compound Library | Hematopoietic Toxicity Compound Library | Anti-COVID-19 Compound Library | FDA-Approved & Pharmacopeia Drug Library | Anti-Cancer Drug Library | Anti-Cancer Clinical Compound Library | Anti-Cancer Approved Drug Library | Apoptosis Compound Library | NO PAINS Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途