化合物Cinanserin hydrochloride T14968
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
1 mL | 54-84-2 | ¥1,460.00 | 询底价 |
100 mg | 54-84-2 | ¥6,960.00 | 询底价 |
25 mg | 54-84-2 | ¥3,470.00 | 询底价 |
5 mg | 54-84-2 | ¥1,320.00 | 询底价 |
50 mg | 54-84-2 | ¥4,990.00 | 询底价 |
1 mg | 54-84-2 | ¥538.00 | 询底价 |
10 mg | 54-84-2 | ¥1,960.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Cinanserin hydrochloride
描述: Cinanserin hydrochloride (SQ 10643) 是一种高亲和力拮抗剂,对 5-HT2 受体的Ki 值为 41 nM。它也是严重急性呼吸综合征冠状病毒的 3C 样蛋白酶抑制剂。
体外活性: Cinanserin and Cinanserin hydrochloride inhibit the catalytic activity of SARS-CoV 3CLpro and HCoV-229E 3CLpro (IC50: 4.68 μM and 5.68 μM). Cinanserin/Cinanserin hydrochloride has a binding affinity to SARS-CoV 3CLpro, HCoV-229E 3CLpro, with the KD values of 49.4 μM/78.0 μM for SARS-associated coronavirus (SARS-CoV) 3CLpro[1].
体内活性: Cinanserin (5 mg/kg; intravenous injection; for 2 hours; male Wistar rats) treatment significantly reduces systemic burn edema to shamburn levels[2].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 125 mg/mL (331.62 mM)
H2O : 100 mg/mL (265.29 mM)
关键字: edema | replication | Serotonin Receptor | Cinanserin hydrochloride | leukocyte | virus | burn | 3C-like | Cinanserin Hydrochloride | proteinase | endothelial | Influenza Virus | Cinanserin | SQ-10643 | Inhibitor | 5-hydroxytryptamine Receptor | systemic | 5-HT Receptor | inhibit | 5-HT2 | SQ10643
相关产品: Tulobuterol hydrochloride | Oplodiol | Baloxavir | 5-Aminouridine | Geniposide | GSK 650394 | Tubercidin | N-(1-benzyl-4-piperidyl)adamantane-1-carboxamide | Picroside II | Glycitin
相关库: Anti-Neurodegenerative Disease Compound Library | Anti-Cancer Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Neuronal Signaling Compound Library | GPCR Compound Library | Inhibitor Library | NO PAINS Compound Library | Anti-Infection Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途