达尔卓潘 T15049

Product Introduction
Bioactivity


英文名: Daltroban

描述: Daltroban (SKF 96148) (BM-13505) 是选择性和特异性的血栓素 A2 (TXA2) 受体拮抗剂。Daltroban 可以增加血管平滑肌细胞内钙。Daltroban 显示对再灌注损伤的保护作用。

体内活性: Daltroban (20 mg/kg per hour i.v.) reduces the ischaemia-induced rise in the ST segment and prevented the development of a Q-wave in the ECG during reperfusion, in comparison with vehicle (physiological saline)-treated cats. Daltroban (1 mg/kg; i.v.; per hour) exerts protective effect in reperfusion injury following acute myocardial ischemia in cats[2]. Daltroban protects the myocardium from ischaemic injury and that this effect involves prevention of ischaemia-induced leukocytosis[3].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 50 mg/mL (141.31 mM)


关键字: SKF96148 | Daltroban | BM 13505 | SKF-96148 | BM13505

相关产品: Protopanaxatriol | CP-868388 free base | Sakuranetin | Sulotroban potassium | Seladelpar | Lanifibranor | Caulophyllogenin | Clofibrate | Methyl oleanonate | 5-Aminosalicylic Acid

相关库: Bioactive Compounds Library Max | Nuclear Receptor Compound Library | DNA Damage & Repair Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途