脱氢阿霉素 T15094
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
25 mg | 31186-13-7 | ¥10,600.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Dehydroaltenusin
描述: Dehydroaltenusin is a selective eukaryotic DNA polymerase α inhibitor and a type of antibiotic produced by a fungus (IC50: 0.68 μM). Dehydroaltenusin inhibits mammalian pol α activity.
体外活性: Dehydroaltenusin (38.0 μM; 6 hours) inhibits cell growth by blocking the S-phase of DNA replication. Dehydroaltenusin (38.0-44.4 μM; 24 hours) inhibits cell growth in a dose-dependent manner (LD50s: 38.0 to 44.4 μM). Dehydroaltenusin (75.0 μM; 24 hours) has a potent apoptotic effect on human cancer cells, DNA ladders can be detected after 12 h of incubation with dehydroaltenusin.
体内活性: Dehydroaltenusin possesses anti-tumor activity against human adenocarcinoma tumors in vivo. Dehydroaltenusin (injection; 20 mg/kg; 2-day intervals; 12-39 days) shows suppressed tumor growth from 21 days.
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: Dehydroaltenusin
相关产品: Moloney murine leukemia virus RT | Remdesivir | APE1-IN-1 | Holomycin | IDD388 | Communic acid | TH287 hydrochloride | Torilin | Osalmid | WRN inhibitor 1
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途