化合物 T15369 T15369
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
2 mg | 6729-55-1 | ¥252.00 | 询底价 |
10 mg | 6729-55-1 | ¥578.00 | 询底价 |
5 mg | 6729-55-1 | ¥413.00 | 询底价 |
25 mg | 6729-55-1 | ¥985.00 | 询底价 |
Product Introduction
Bioactivity
英文名: gamma-DGG
描述: gamma-DGG is a competitive blocker of AMPA receptor.
体外活性: gamma-DGG (γ-DGG) is the most effective antagonist of the excitatory postsynaptic potentials (e.p.s.p.s). Its action is reversible and not associated with any change in the passive membrane properties of the granule cells or in the apparent reversal potential of the e.p.s.p.gamma-DGG blocks less at higher glutamate concentration. gamma-DGG (200-400 μM) in the bath decreases the miniature EPSC (mEPSC) amplitude by 26±2% (n=5 synapses) and shifts both the mEPSC amplitude distribution and the cumulative probability curve to the left [1]. The quantal analysis displays that the reduction in the e.p.s.p. paralleled the reduction in quantal size rather than quantal content, confirming a post-synaptic site of the action of gamma-DGG [2].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: H2O : 150 mg/mL (734.65 mM)
关键字: gamma-DGG | gamma-D-Glutamylglycine | rDGG | r-D-Glutamylglycine | gamma DGG | gammaDGG
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途