化合物 T15813 T15813

Product Introduction
Bioactivity


英文名: LY309887

描述: LY309887 is a potent inhibitor of glycinamide ribonucleotide formyltransferase (Ki: 6.5 nM). It also has antitumor activity.

体外活性: LY309887 is significantly cytotoxic against the human leukemia cell line CCRF-CEM (IC50: 9.9 nM). LY309887 also has high affinity at human folate receptor (FR)α and FRβ (Ki, 1.78 nM, and 18.2 nM, respectively) .

体内活性: In mice bearing C3H mammary cancer cells, LY309887 (3 mg/kg-100 mg/kg, i.p.) displays complete inhibition on the tumor growth.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

关键字: LY309887 | LY 309887 | LY-309887

相关产品: γ-Linolenic Acid methyl ester | Montelukast sodium | Bunaprolast | Darbufelone | BIRM 271 | Fiboflapon sodium | Diffractaic Acid | Pranlukast | Acebilustat | Veliflapon

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途