化合物LY518674 T15821

Product Introduction
Bioactivity


英文名: LY518674

描述: LY518674 (LY-674) 是一种高效、选择性的 PPARα 激动剂，对人 PPARα 作用的 EC50 值为 42 nM。LY518674 能降低甘油三酸酯，增加 HDL-C，可用于研究动脉粥样硬化。

体内活性: LY518674 decreases triglycerides and increased HDL-C in vivo[2]. LY518674 significantly enhances apolipoprotein A-I (apoA-I) turnover without a major impact on steady-state levels of apoA-I or high-density lipoprotein-cholesterol (HDL-C) [3].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 250 mg/mL (610.53 mM)


关键字: Peroxisome proliferator-activated receptors | inhibit | PPAR | Inhibitor | LY-518674 | LY518674 | LY 674 | PPARα | atherosclerosis | LY674 | LY 518674

相关产品: Fonadelpar | SC-236 | Ankaflavin | CRX000227 | GW9662 | GW 9578 | Bavachinin | FH535 | DG172 dihydrochloride | Inolitazone

相关库: Drug Repurposing Compound Library | Anti-Breast Cancer Compound Library | Transcription Factor-Targeted Compound Library | Mitochondria-Targeted Compound Library | Anti-Cancer Drug Library | Clinical Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Anti-Cancer Clinical Compound Library | Anti-Obesity Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途