化合物 T16035 T16035
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
5 mg | 71751-77-4 | ¥9,990.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Meleagrin
描述: Meleagrin, a roquefortine C-derived alkaloid produced by Penicillium fungi, serves as both a class of FabI inhibitors and a lead c-Met inhibitory entity for controlling c-Met-dependent metastatic and invasive breast malignancies. It exhibits antimicrobial and anti-proliferative activities.
体外活性: Meleagrin induces a dose-dependent inhibition of HGF-induced cell migration, and invasion of breast cancer cell lines. Meleagrin suppresses the growth of the human breast cancer cell lines MDA-MB-231, MDA-468, BT-474, SK BR-3, MCF7 and MCF7-dox [3].
体内活性: In an orthotopic athymic nude mice model, Meleagrin effectively inhibits the invasive triple-negative breast tumor cell growth[3].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: Meleagrin
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途