化合物ML349 T16108
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
2 mg | 890819-86-0 | ¥593.00 | 询底价 |
1 mg | 890819-86-0 | ¥415.00 | 询底价 |
25 mg | 890819-86-0 | ¥3,370.00 | 询底价 |
100 mg | 890819-86-0 | ¥6,860.00 | 询底价 |
50 mg | 890819-86-0 | ¥4,890.00 | 询底价 |
10 mg | 890819-86-0 | ¥1,590.00 | 询底价 |
500 mg | 890819-86-0 | ¥13,800.00 | 询底价 |
1 mL | 890819-86-0 | ¥987.00 | 询底价 |
5 mg | 890819-86-0 | ¥947.00 | 询底价 |
Product Introduction
Bioactivity
英文名: ML349
描述: ML349 是一种特异性酰基蛋白硫酯酶 2 /溶血磷脂酶 2 抑制剂,其Ki=120 nM。它也是一种 LYPLA2的抑制剂,其IC50=144 nM。
体外活性: ML349 is an inhibitor of both LYPLA1 and LYPLA2 with IC50s of >3000 and 144 nM, respectively. ML349 also is an inhibitor of acyl protein thioesterase 1 and 2 (APT-1 and APT-2) with Kis of >10000 and 120±20 nM, respectively. ML348 and ML349 do not reduce cell viability, but they cause a slight activation of AKT in NRAS mutant cells[1][2][3].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 20 mg/mL (44.00 mM)
关键字: Inhibitor | inhibit | Phospholipase | ML-349 | ML 349 | ML349
相关产品: Carbazochrome | Melittin TFA(20449-79-0(free base)) | hnps-PLA Inhibitor | VU0364739 | PACOCF3 | Rhamnetin | CAY10594 | Melittin Acetate | Varespladib | RPI-1
相关库: Bioactive Compounds Library Max | Inhibitor Library | Anti-Obesity Compound Library | Lipid Metabolism Compound Library | Metabolism Compound Library | Bioactive Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途