普马拉唑 T16682

Product Introduction
Bioactivity


英文名: Pumaprazole

描述: Pumaprazole (BY-841) 是一种有效的、可逆的质子泵拮抗剂。

体内活性: Pumaprazole shows identical ID50 values on day 1 (11 μmol/kg, 95% confidence limits of 5 and 23), and on day 7 (10 μmol/kg, 95% confidence limits of 4 and 23) of a repeated dose study in this model. Basal acid secretion in the Ghosh-Schild rat is inhibited by Pumaprazole with a higher efficacy compared to ranitidine. The lower dose of Pumaprazole (27 μmol/kg) rapidly elevates luminal pH up to almost neutrality, the higher dose (54 μmol/kg) further prolongs this pH-elevating effect[1].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 55 mg/ml (162.53 mM)


关键字: inhibit | Pumaprazole | Proton Pump | BY841 | BY 841 | Inhibitor

相关产品: Esomeprazole Magnesium | Lansoprazole Sulfide D4 | Omeprazole Sodium | Abeprazan hydrochloride | Pantoprazole Sodium Hydrate | Pantoprazole sodium | Levolansoprazole | Tegoprazan | Saviprazole | Lansoprazole

相关库: ReFRAME Related Library | Anti-Cancer Compound Library | Membrane Protein-targeted Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Exosome Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途