辛伐他汀铵盐 T16885
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
2 mg | 139893-43-9 | ¥252.00 | 询底价 |
25 mg | 139893-43-9 | ¥1,280.00 | 询底价 |
10 mg | 139893-43-9 | ¥663.00 | 询底价 |
1 mL | 139893-43-9 | ¥455.00 | 询底价 |
5 mg | 139893-43-9 | ¥413.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Simvastatin acid ammonium
描述: Simvastatin ammonium is an active metabolite of simvastatin lactone mediated. Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 gene.
体外活性: The Michaelis-Menten constant (Km) for simvastatin acid uptake by OATP3A1 was 0.017 μM and the Vmax was 0.995 fmol/min/105 cells. There is a pH-dependent effect on organic anion transporting polypeptide 3A1 uptake, with more efficient simvastatin acid uptake at pH5.5 in HEK293 cells transfected with the OATP3A1 gene [1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
关键字: Simvastatin acid ammonium
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途