孕二烯二酮 T17280
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
10 mg | 39025-23-5 | ¥1,587.00 | 询底价 |
100 mg | 39025-23-5 | ¥5,890.00 | 询底价 |
50 mg | 39025-23-5 | ¥4,140.00 | 询底价 |
25 mg | 39025-23-5 | ¥3,208.00 | 询底价 |
1 mL | 39025-23-5 | ¥1,180.00 | 询底价 |
5 mg | 39025-23-5 | ¥997.00 | 询底价 |
Product Introduction
Bioactivity
英文名: (Z)-Guggulsterone
描述: (Z)-Guggulsterone 是印度阿育吠陀药用植物Commiphora mukul 的成分,可通过引起细胞凋亡来抑制人前列腺癌细胞的生长,还可通过抑制VEGF-VEGF-R2-Akt 信号传导轴来抑制血管生成。
体外活性: In HUVEC, Z-guggulsterone (10, 20 μM; 24 or 48 hours) induces a reduction in the level of VEGF-R2 protein [1].
体内活性: In tumor volume and wet tumor weight, Z-guggulsterone (p.o.; 1 mg; 5 times/week) causes a statistically significant reduction [1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 10 mg/mL (32.01 mM)
关键字: inhibit | VEGFR | Protein kinase B | PKB | Inhibitor | Guggulsterone | (Z)-Guggulsterone | (Z) Guggulsterone | Vascular endothelial growth factor receptor | Akt | (Z)Guggulsterone | Apoptosis
相关产品: CP 461 | Bufotalin | Scoulerine | Lawsone methyl ether | Polyphyllin II | ranaconitine | Furanodiene | Vesatolimod | PRMT6-IN-3 | Fosbretabulin Disodium
相关库: Antioxidant Compound Library | PI3K-AKT-mTOR Compound Library | Glutamine Metabolism Compound Library | Selected Plant-Sourced Compound Library | Membrane Protein-targeted Compound Library | Inhibitor Library | Kinase Inhibitor Library | Anti-Cancer Active Compound Library | Tyrosine Kinase Inhibitor Library | Apoptosis Compound Library
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途