化合物Thalidomide-O-amido-PEG2-C2-NH2 TFA T17918

Product Introduction
Bioactivity


英文名: Thalidomide-O-amido-PEG2-C2-NH2 TFA

描述: Thalidomide-O-amido-PEG2-C2-NH2 TFA (E3 Ligase Ligand-Linker Conjugates 24 TFA) 包含基于 Thalidomide 的 cereblon 配体和 2 个单元的 PEG linker，是一种合成的 E3 连接酶配体-linker 偶联物。

体外活性: PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

存储条件: keep away from direct sunlightPowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: H2O : 150 mg/mL (260.20 mM)


关键字: Thalidomide O amido PEG2 C2 NH2 TFA | Cereblon Ligand-Linker Conjugates 10 | E3 Ligase Ligand-Linker Conjugates 24 | Inhibitor | Thalidomide-O-amido-PEG2-C2-NH2 TFA | inhibit | Thalidomide-O-amido-PEG-2-C2-NH2 TFA | ThalidomideOamidoPEG2C2NH2 TFA | E3 Ligase Ligand-Linker Conjugates

相关产品: Thalidomide-NH-C6-NH2 hydrochloride | Thalidomide-O-C4-NH2 hydrochloride | (S,R,S)-AHPC-PEG3-NH2 hydrochloride | Thalidomide-NH-PEG1-NH2 hydrochloride | Thalidomide-O-C6-NH2 hydrochloride | Thalidomide-NH-C2-PEG3-OH | (S,R,S)-AHPC-PEG3-N3 | Thalidomide 4'-ether-alkylC2-amine hydrochloride | Thalidomide-O-amido-PEG3-C2-NH2 TFA | Pomalidomide-PEG4-C-COOH

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途