化合物KX1-004 T1812
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
50 mg | 518058-84-9 | ¥3,930.00 | 询底价 |
10 mg | 518058-84-9 | ¥1,630.00 | 询底价 |
5 mg | 518058-84-9 | ¥913.00 | 询底价 |
25 mg | 518058-84-9 | ¥2,750.00 | 询底价 |
1 mg | 518058-84-9 | ¥378.00 | 询底价 |
100 mg | 518058-84-9 | ¥5,730.00 | 询底价 |
500 mg | 518058-84-9 | ¥11,500.00 | 询底价 |
1 mL | 518058-84-9 | ¥983.00 | 询底价 |
2 mg | 518058-84-9 | ¥546.00 | 询底价 |
Product Introduction
Bioactivity
英文名: KX1-004
描述: KX1-004 是非 ATP 竞争性 Src-PTK 抑制剂,IC50=40 μM。它能够保护耳蜗,使其免受有害噪音的影响,并防止噪音引起的听力损失 (NIHL)。
激酶实验: The Lck HTRF kinase assay involves ATP-dependent phosphorylation of a biotinylated substrate peptide of gastrin in the presence or absence of inhibitor compound. The final concentration of gastrin is 1.2 μM. The final concentration of ATP is 0.5 μM (Km app =0.6±0.1 μM), and the final concentration of Lck (a GST-kinase domain fusion (AA 225?509)) is 250 pM. Buffer conditions are as follows: 50 mM HEPES pH=7.5, 50 mM NaCl, 20 mM MgCl2, 5 mM MnCl2, 2 mM DTT, 0.05% BSA. The assay is quenched and stopped with 160 μL of detection reagent. Detection reagents are as follows: Buffer made of 50 mM Tris, pH=7.5, 100 mM NaCl, 3 mM EDTA, 0.05% BSA, 0.1% Tween20. Prior to reading, Streptavidin allophycocyanin (SA-APC) is added at a final concentration in the assay of 0.0004 mg/mL, along with europilated anti-phosphotyrosine Ab (Eu-anti-PY) at a final conc of 0.025 nM. The assay plate is read in a Discovery fluorescence plate reader with excitation at 320 nm and emission at 615 and 655 nm[1].
存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : 60 mg/mL (211.05 mM)
关键字: noise | cells | inhibit | Src | hearing | exposure | Inhibitor | KX 1004 | KX-1004 | KX1-004 | loss | KX-1-004 | hair
相关产品: Dasatinib hydrochloride | MCB-613 | A-443654 | BT424 | Ibrutinib | CGP77675 | NVP-BHG712 | OSI-930 | CHIR-98014 | ARN25068
相关库: HIF-1 Signaling Pathway Compound Library | Bioactive Compounds Library Max | Fluorochemical Library | Inhibitor Library | Kinase Inhibitor Library | Tyrosine Kinase Inhibitor Library | Anti-Pancreatic Cancer Compound Library | Target-Focused Phenotypic Screening Library | NO PAINS Compound Library | Bioactive Compound Library
化合物KX1-004 T1812信息由TargetMol中国为您提供,如您想了解更多关于化合物KX1-004 T1812报价、型号、参数等信息,欢迎来电或留言咨询。
注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途