化合物TTP 22 T1828

Product Introduction
Bioactivity


英文名: TTP 22

描述: TTP 22 是一种高亲和力、ATP 竞争性酪蛋白激酶 2 抑制剂，IC50和 Ki 值分别为 0.1 uM 和 40 nM。

激酶实验: PI3K biochemical assay (ATP depletion assay): BKM120 is dissolved in DMSO and directly distributed into a black 384-well plate at 1.25 μL per well. To start the reaction, 25 μL of 10 nM PI3 kinase and 5 μg/mL 1-α-phosphatidylinositol (PI) in assay buffer (10 mM Tris pH 7.5, 5 mM MgCl2, 20 mM NaCl, 1 mM DTT and 0.05% CHAPS) are added into each well followed by 25 μL of 2 μM ATP in assay buffer. The reaction is performed until approx 50% of the ATP is depleted and then stopped by the addition of 25 μL of KinaseGlo solution. The stopped reaction is incubated for 5 minutes and the remaining ATP is then detected via luminescence.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 50 mg/mL (151.32 mM)


关键字: TTP-22 | Casein Kinase | Inhibitor | TTP 22 | inhibit | TTP22

相关产品: Longdaysin | CK1-IN-2 | CKI-7 free base | IWP-2 | Casein Kinase inhibitor A51 | MLN8054 | CK1-IN-1 | XL413 hydrochloride | WAY-297174 | BMS-863233 HCl

相关库: Anti-Aging Compound Library | Wnt/Hedgehog/Notch Compound Library | Bioactive Compounds Library Max | Inhibitor Library | Kinase Inhibitor Library | Metabolism Compound Library | Target-Focused Phenotypic Screening Library | Stem Cell Differentiation Compound Library | NO PAINS Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途