化合物Hoechst 34580 T19011

Product Introduction
Bioactivity


英文名: Hoechst 34580

描述: Hoechst 34580 (HOE 34580) 是细胞渗透性荧光染料，可用于 DNA 和核染色。

体外活性: Hoechst 34580 is a good candidate for treating Alzheimer's disease by inhibiting Aβ formation. 50 μM Aβ42 solutions co-incubated with 100, 25, 12.5, 3.125, 0.78, and 0.1, 0.01 μM Hoechst 34580 at 37 °C for 70 h. Hoechst 34580 can inhibit the aggregation of Aβ42 in a dose-dependent manner. The IC50 is obtained by measuring the concentration of Hoechst 34580 while maintaining the Aβ42 concentration which gave 0.86±0.05 μM for Hoechst 34580.

存储条件: keep away from direct sunlightPowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 47 mg/mL (104.08 mM)


关键字: β-amyloid peptide | Hoechst34580 | HOE34580 | Inhibitor | Hoechst 34580 | HOE-34580 | Amyloid-β | Hoechst-34580 | inhibit | Abeta

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途