Seco雷帕霉素钠盐 T19558

Product Introduction
Bioactivity


英文名: Seco Rapamycin sodium salt

描述: Seco Rapamycin sodium salt is a ring-opened product of Rapamycin.

体外活性: When applied to the apical compartment, little Seco Rapamycin is detected in the basolateral compartment and in the cellular fraction after 4 h. In addition, little M2 is detected. LY335979 has little effect on the distribution of Seco Rapamycin after an apical dose, although M2 became detectable in the apical compartment. In contrast, when Seco Rapamycin is applied to the basolateral compartment, both Seco Rapamycin and M2 are readily detected in the apical compartment; LY335679 decreases the flux of Seco Rapamycin to the apical compartment and increases the amount of M2 in both apical and basolateral compartments.

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 46 mg/mL (49.14 mM)


关键字: Secorapamycin A | Seco Rapamycin sodium | Seco Rapamycin sodium salt

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