环(L-色氨酰-L-色氨酰) T19717

Product Introduction
Bioactivity


英文名: Cyclo-L-Trp-L-Trp

描述: Cyclo-L-Trp-L-Trp 是一种广谱抗真菌剂。它还诱导组蛋白的高度乙酰化。

体外活性: Two novel cyclic hexapeptides designated actinosynneptides A (1) and B (2), together with three tryptophan containing diketopiperazines, namely cyclo(L-Trp-L-Trp) (3), cyclo(L-Trp-N-MeL-Trp) (4), and cyclo(N-MeL-Trp-N-MeL-Trp) (5), were isolated from the culture of the genetically engineered strain HGF052::asm18 derived from Actinosynnema pretiosum ATCC31565. Their structures were elucidated on the basis of spectroscopic analyses and single-crystal X-ray diffractions. Compound 1 is the first example of 3-amino-6-hydroxy-2-piperidone-containing cyclic peptides, and 1 and 2 showed moderate cytotoxic activities against HeLa and PC3 cell lines[1].

存储条件: keep away from moisturePowder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: DMSO : 30 mg/mL (80.56 mM)


关键字: Staphylococcus aureus | Cyclo-L-Trp-L-Trp | Micrococcus luteus | inhibit | Bacillus subtilis | Antibiotic | A. baumannii | Inhibitor | CycloLTrpLTrp | Candida albicans | Cyclo L Trp L Trp | Saccharomyces cerevisiae | antimicrobial activity | Bacterial | Aspergillus niger

相关产品: Xanthone | Climbazole | Filipin complex | NB-598 hydrochloride | (+)-Magnoflorine iodide | Geraniol | Lanoconazole | Caerulomycin A | Rapamycin | NH125

相关库: Bioactive Compounds Library Max | Anti-Fungal Compound Library | NO PAINS Compound Library | Anti-Infection Compound Library | Bioactive Compound Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途