甲基条叶蓟素 T19886
品牌 | 厂商性质 | 产地 | 货期 |
---|---|---|---|
TargetMol | 生产商 | 美国 | 现货 |
性能特点
生化试剂,可用于动物细胞实验
规格 | CAS号 | 价格 | 操作 |
---|---|---|---|
5 mg | 41365-32-6 | ¥12,300.00 | 询底价 |
Product Introduction
Bioactivity
英文名: Cirsilineol
描述: Cirsilineol (Eupatrin) 是从 Artemisia vestita Wall 的草本植物中分离出来的,具有免疫抑制、抗增殖和抗肿瘤特性。 Cirsilineol 通过线粒体途径选择性诱导细胞凋亡。
体外活性: Cirsilineol (0.1, 1, 10 μM) dose-dependently inhibits single mixed lymphocyte reaction and the proliferation of Concanava A-induced T-cells in Splenocytes. Cirsilineol (1, 5, 10 μM) inhibits IFN-γ-induced Tyr701 phosphorylation of STAT1 and the activation of JAK2 in Splenic CD4+ T cells[3].
体内活性: In female C57BL/6, BALB/c, and DO11.10 transgenic mice with TNBS, Cirsilineol (3-30 mg/kg) reduces inflammatory infiltration, restores the destructive mucosal architecture, and remisses edema thus improving the effects on the body weights and survival rate of mice. Cirsilineol ameliorates TNBS-induced Th1-mediated colitis by inhibiting IFN-γ/STAT1/T-bet signaling in CD4+ T cells[1].
存储条件: store at low temperature,keep away from direct sunlightPowder: -20°C for 3 years | In solvent: -80°C for 1 year
溶解度: DMSO : Soluble
关键字: SPM-927 | Cirsilineol | SPM927
相关产品: Polydatin | Demethylzeylasteral | PHA-665752 | Tivantinib | AZA1 | FLLL32 | Bacopaside II | Epothilone A | Xevinapant hydrochloride | Nitidine chloride
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注:该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案,不可用于临床诊断或治疗等相关用途