盐酸土霉素 T21430

Product Introduction
Bioactivity


英文名: Oxytetracycline Hydrochloride

描述: Oxytetracycline Hydrochloride (Dalimycin) 是由 Streptomyces rimosus 生产的，一种具有抗菌活性的四环素衍生物。它干扰氨酰-tRNA 与 mRNA-核糖体复合物的结合，从而阻止肽延伸并抑制蛋白质合成。

体内活性: The 10-day effect of oxytetracycline at therapeutic doses (82.8 mg/kg bw to 1 % bw/day) was species-specific. Oxytetracycline increases the enzymatic activity of CYP3A4 in Ictalurus punctatus, increases the protein expression of CYP3A4 in Oreochromis niloticus, and depletes hepatic CYP3A4 in the latter, and also increases the relative liver weight of Morone chrysops x M. saxatilis [1]. Oxytetracycline is limited to 100 μg/kg in muscle and breast milk, 200 μg/kg in eggs, 300 μg/kg in liver, and 600 μg/kg in kidney[3].

存储条件: Powder: -20°C for 3 years | In solvent: -80°C for 1 year

溶解度: H2O : Insoluble
DMSO : 60 mg/mL (120.75 mM)


关键字: Oxytetracycline Hydrochloride | Gram-positive | Antibiotic | Oxytetracycline | Gram-negative | Bacterial | tetracycline | Herpes simplex virus | Inhibitor | synthesis | Endogenous Metabolite | protein | HSV-1 | m-ribosomal | HSV | inhibit | aminoacil-tRNA

相关产品: IM-250 | Compound TN1582(SC) | ERDRP-0519 | pocapavir | DDG-39 | 3'-Azido-3'-deoxy-5-methylcytidine | Carrageenan | GS-9191 PM | Antiviral agent 38 | Edoxudine

相关库: FDA-Approved Drug Library | Drug Repurposing Compound Library | Bioactive Compounds Library Max | Human Metabolite Library | Human Endogenous Metabolite Compound Library Plus | Natural Product Library for HTS | Microbial Natural Product Library | Anti-Viral Compound Library | Anti-infective Natural Product Library | Natural Product Library

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注：该产品未在中华人民共和国食品药品监督管理部门申请医疗器械注册和备案，不可用于临床诊断或治疗等相关用途